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KMID : 0369819940240010025
Jorunal of Korean Pharmaceutical Sciences
1994 Volume.24 No. 1 p.25 ~ p.28
Migration of Water - Soluble Vitamins into Gelatin Layer of Soft Capsules
¿À¼¼Á¾/Oh SJ
¹Ú¿øÈñ/À±±¤Àç/À±¿ø¿ë/Park WH/Yun KJ/Yoon WY
Abstract
The previous vitamin assays in soft capsules have been performed only with capsule contents. Since some vitamins, however, could migrate into gelatin layer of the soft capsules, each vitamin of multivitamin soft capsules in the market was analyzed simultaneously in both capsule content and gelatin layer. The results showed that migrations of nicotinamide and pyridoxine hydrochloride into gelatin layer were pronounced, while those of other vitamins were negligible.
KEYWORD
Water-soluble vitamins, Soft capsules, Migration
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